• Dr Sophia Karagiannis and her team

    Antibody therapy and biomarker discovery team

    Triple negative breast cancer is a sub-type of the disease for which there are currently no targeted treatments. In addition, this form of breast cancer can be more aggressive than others.

  • Breast cancer stem cells Dr Robert Clarke

    Breast cancer stem cells

    There is still so much we need to know about how breast cancer cells escape from the original breast tumour, enter the blood stream and manage to seed new tumours in places such as the bone, lungs and brain.

  • Breast Development team

    Breast Development team

    Although effective treatments for breast cancer exist, there are many patients for whom these treatments don’t work or stop working over time.

  • Cell Death and Inflammation Team

    Cell Death and Inflammation Team

    Cancer cells are extremely resilient and able to survive in harsh conditions, sometimes lingering in the body even after treatment. Finding ways to tackle this resilience will help scientists develop more effective ways to treat breast cancer.

  • Nick Orr

    Complex Trait Genetics Group

    The best way to stop people dying from breast cancer is to stop it occurring in the first place. To do this, we need to be able to identify those most at risk of breast cancer and work out what we can do to prevent them from developing it.

  • Developing a breast cancer vaccine

    Developing a breast cancer vaccine

    Radiotherapy and chemotherapy currently used to treat breast cancer can have harmful side effects. Researchers are developing new therapies that aim to stimulate the body’s immune system to attack and kill breast cancer cells, called ‘immunotherapies’

  • Developing a virus treatment for triple negative breast cancer

    Developing a virus treatment for triple negative breast cancer

    Triple negative breast cancer is a form of the disease which has limited treatment options because it cannot be treated using targeted therapies available for other types of breast cancer.

  • Dr Penelope Ottewell and her team

    Developing new models that mimic the spread of breast cancer to the bones

    Dr Ottewell will develop new models that mimic how cancer cells spread from the breast to the bones in humans.

  • Developing new ways to assess treatment for breast cancer spread to the bone

    Developing new ways to assess treatment for breast cancer spread to the bone

    When breast cancer spreads to the bone, patients can experience severe symptoms such as pain and bone fractures. Having secondary cancer reduces the chance of survival.

  • Drug Target Discovery team - Prof Spiros Linardopoulos

    Drug Target Discovery team

    Although effective treatments exist for breast cancer, there are many patients for whom these drugs don’t work or stop working over time. We need to develop the next generation of targeted drugs to ensure that all patients receive the best possible treatment.

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