Professor Awen Gallimore hopes to target two types of cells inside breast tumours that can stop the immune system from effectively destroying breast cancer cells. This approach could lead to a new immunotherapy to treat breast cancer.

Professor Kristijan Ramadan is hoping to understand why some breast cancers become resistant to a breast cancer treatment called PARP inhibitors, and is looking for new ways to overcome this resistance.

Breast cancer stem cells are thought to be responsible for some breast cancers developing resistance to treatment, and may cause breast cancer to spread. Dr Paloma Garcia wants to find out more about how we can target these cells to stop breast cancer spreading.

Miss Karina Cox is investigating whether a special ultrasound method can help specialists find out if breast cancer has spread to the lymph nodes in the armpit.

Dr Jason Carroll is investigating what role the gene ARID1A plays in breast cancer spreading around the body. He also aims to understand if a class of drugs called BET inhibitors could be used to treat secondary breast cancer that has changes in this gene.

There are currently few targeted treatments available for triple negative breast cancer. In addition, it can be more aggressive than other breast cancers. We need to understand what makes triple negative breast cancer different from other forms of the disease to develop new effective targeted treatments for patients.