Applications are now closed.

In 2013, Breast Cancer Now identified a need for research that would better identify women at high risk of breast cancer, and that would lead to interventions to reduce their risk. The challenges were highlighted in the publication “Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer”1. These challenges still remain to be addressed.

Our aim

Breast Cancer Now’s strategy (PDF) shows how we want to help prevent breast cancer and stop deaths from breast cancer by:

  • Supporting efforts to create a more refined risk-adapted screening programme, in addition to screening based on gender and age
  • Developing research and interventions that reduce the risk of breast cancer
  • Supporting women who attend breast screening to take action to reduce their risk of breast cancer

Our research is contributing to developing and improving the risk assessment and interventions for women in different breast cancer risk categories. We want to extend this by funding more research into interventions to reduce the risk of breast cancer in those identified at higher risk.

In the longer term we want to support more research to integrate appropriate prevention interventions within different categories, and to make clinicians and the public more aware of the benefits and potential side effects of different interventions.

We will consider funding research projects in but not limited to the following areas:

  • Communicating breast cancer risk
  • Developing and testing behaviour change interventions around lifestyle factors such as weight, activity or alcohol consumption
  • Introducing lifestyle modification programs to the breast screening programme, including increased physical activity, avoidance of weight gain, avoidance of harmful consumption of alcohol and encouragement of breastfeeding
  • Identifying and testing new options for chemoprevention
  • Overcoming barriers to prevention interventions, including understanding the challenges of adherence to chemoprevention
  • Novel approaches such as mimicking hormonal changes to offer protection against post-menopausal breast cancer

We will give priority to projects that are likely to have the largest potential impact on preventing cases of breast cancer.

Although we are unable to support large randomised control trials, we can support pilot studies in support of a larger trial. We would be open to potential partnerships with others to jointly fund larger trials.

Applications from multidisciplinary groups are particularly encouraged.

We will accept applications from established researchers with a strong track record, based at an eligible academic research institution in the UK. Please note that we are unable to accept applications for PhD studentships.

We anticipate funding one or two projects in this round. Applications may be of any duration, but must not exceed £300,000 in total. We will consider joint funding of a project, with Breast Cancer Now’s contribution being up to the maximum value stated.

Please contact us if you wish to discuss this option.

The closing date for applications was 1 March 2019.

Applications received will be reviewed by our Risk and Prevention Committee and applicants will be informed of the outcome of their application by mid-August 2019.

1 Eccles et al. (2013) Breast Cancer Research 15:R92, available online at BioMed Central