Professor Lewis will investigate whether targeting two molecules, CXCR4 and VEGFA, can prevent relapse and the development of secondary tumours in triple negative breast cancer.

 

Dr Georgia Mavria is studying how a molecule called DOCK4 is involved in the spread of breast cancer to the brain. Her work could lead to new ways to prevent secondary tumours from growing in the brain and ultimately save lives.

 

Breast tumours can sometimes become resistant to treatment. Dr Yinyin Yuan will find out how the non-cancer cells that surround tumours help them develop resistance to avoid this. 

 

Prof Jo Morris is investigating a new role for the BRCA1 protein, which could lead to new ways to predict and prevent breast cancer.

 

Professor Robert Clarke is studying how a molecule called IL 1β helps breast cancer spread to the bones.

 

Professor Robert Clarke hopes to understand how ‘sleeping’ cancer stem cells awaken and find ways to stop this happening.