Professor Ian Kunkler is investigating the impact that an additional, targeted booster dose of radiotherapy has on preventing DCIS from returning and developing into invasive breast cancer, and the effects it has on breast appearance and quality of life.

Dr Nora Pashayan would like to find the best way to personalise the breast screening programme, adjusting screening timing and frequency according to a woman’s individual risk, in order to maximise the benefits and minimise the potential harms of screening.

Dr Seth Coffelt is investigating how a specific type of white blood cell can help breast cancer to spread throughout the body. His work could lead to new ways to prevent the spread of breast cancer, and ultimately stop people dying from the disease.

Dr Powis is investigating proteins that are released by breast cancer cells, to determine how they might be affecting the ways in which the immune system recognises and kills cancer, and how we could use this knowledge to improve treatment for breast cancer patients.

Professor Emad Rakha is developing an innovative new method of detecting the presence of cancer cells in the lymph nodes that surround the breast. This new method could be a more accurate and faster way to determine whether patients could benefit from the removal of these lymph nodes at the same time as initial breast tumour surgery.

Breast cancer that has spread to the brain can be particularly hard to treat and severely affects people’s quality of life. Walk the Walk Fellow Dr Damir Varešlija is looking at how gene switches in breast cancer cells might make them more likely to spread to the brain and hopes to find ways to stop this from happening.