Breast cancer is not one, but a collection of diverse and overlapping diseases. This makes it difficult to accurately diagnose patients and select the best possible treatment for each individual.

Although effective treatments exist for breast cancer, there are many patients for whom these drugs don’t work or stop working over time. 

The Molecular Cell Biology team are studying the cellular mechanisms that control the growth and spread of tumour cells.

Breast cancer is an incredibly diverse and complex disease, which means treatments that work for one patient won’t necessarily work for another. We need to identify the best way to select patients for the most appropriate treatment so that everyone can benefit from truly personalised medicine.

Women at high risk of developing breast cancer can take chemoprevention drugs, such as tamoxifen, to reduce their risk. However, chemoprevention will be effective for only some women.

We know that our genetics play a key role in determining breast cancer risk, but we need to know much more about the specific genes involved and how they affect an individual person’s risk.