To be able to grow, cancer cells need to divide. But they do this in an abnormal way, which causes the uncontrollable growth of tumours. Professor Judy Coulson is studying this process in more detail, with the hope of developing new therapies to improve survival for patients.

Dr Robert Falconer is developing a new form of chemotherapy, which could only kill cancer cells, leaving healthy cells intact. If this project is successful, it could save lives and lead to more people living beyond breast cancer.

 

Dr Klaus Pors and his PhD student are investigating how to unlock the potential of chemotherapy drugs known as duocarmycins, which could provide a new, more effective treatment option for people with breast cancer – especially those whose cancer has returned or spread.

 

Prof Leonie Young is studying a protein called RET, which is thought to be involved in the spread of breast cancer to the brain. Her work could eventually lead to treatments which can control or even prevent secondary tumours in the brain.

Professor Richard Grose will study two types of cells involved in the progression of DCIS to invasive breast cancer. Understanding them better would help to predict which patients with DCIS will need treatment to stop invasive breast cancer developing.