Professor David French would like to understand whether for women at low risk of breast cancer, the benefits of screening outweigh the potential harms, and if so, whether these women should be offered less frequent screening appointments.

Professor Kaye Williams is investigating whether blocking two proteins simultaneously could reduce the growth and spread of breast cancer. The hope is that her work could bring new treatments to people with aggressive forms of the disease, and in doing so save lives.

Breast cancer can trick our immune system into ignoring it, which can cause cancer cells to grow and spread. Professor Damian Mole’s team is studying one possible way tumours do this, so we can develop new treatments to improve the chances of survival for people with breast cancer.

In the future, breast screening could be adapted to a woman’s personal risk of developing breast cancer, which could change how regularly women are screened. Dr Jo Waller will investigate the concerns women have about this to ensure these approaches are effective.

Dr Seth Coffelt is investigating how a specific type of white blood cell can help breast cancer to spread throughout the body. His work could lead to new ways to prevent the spread of breast cancer, and ultimately stop people dying from the disease.

Breast cancer that has spread to the brain can be particularly hard to treat and severely affects people’s quality of life. Walk the Walk Fellow Dr Damir Varešlija is looking at how gene switches in breast cancer cells might make them more likely to spread to the brain and hopes to find ways to stop this from happening.