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Triple negative breast cancer is a sub-type of the disease for which there are currently no targeted treatments. In addition, this form of breast cancer can be more aggressive than others.
Professor Holen’s team is studying the role of two proteins in breast cancer spread to bone.
Patients with triple negative breast cancer have limited treatment options because their breast tumours lack the receptors which targeted therapies like tamoxifen and Herceptin act against.
Mutations in F-box genes could lead to new treatments for breast cancer patients.
Dr Huang hopes that identifying new weak spots in cancer cells will lead to new treatments.
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